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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'bf998237d8906245765a72865bb7d561321fb3b7be8a70cfccd9a8e192801dc7' 
  AND token = '2259gIX4xKMIEocOdXhZyyqDbVzf8VAJERvqW6LAEkM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00028

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}