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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '7f5ed60f1e9ba2d08b007ce4f012363ade75feb503eca387960ba45c3d5c4dd5' 
  AND token = 'nly/ej9Touq8DGBQ5JaHsxG3lMfYiHjxLa00BqsiVdA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00045

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}