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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '75acbe02403f211608c55a79ea02d5a880a8b42b934369d57b8fae71eb74e0cc' 
  AND token = '0e9LUkj8qAgKeM791LHAVfOcDmQIqVA5CAeagYZ7uik=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00036

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}