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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '439cd2e7c4410ff5c7378d4906254f33425758b9454f1a2a66d51b745d935020' 
  AND token = 'YlLpjAlvrHJuZPMgMBo3hQO3DWWuHVaIt95ytgEatdo=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00033

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}