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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'cfaf2c22e84436dcbe5e1dd6ac037b81d31e745c9604bd06045e9db39bab888b' 
  AND token = '6ZDhBtFBaK5d+44cD8SZ50BHOCK/y7km+mK0yWcwy1k=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00047

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}