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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '72c9c6a7eb78154a20bd543ff2aa8d573a60a25de6d8969eb5471e000dadec1b' 
  AND token = '3iHm5L9Ei2E3lt63FlIiXsORhTJ2TvXQ75Oq5s93L4w=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00032

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}