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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '14975998ddb750a8f4f0b5b8f1d43d247308c25d62cbbf321df8e514acd8442c' 
  AND token = 'KNEFhViKFMYrAjaC05tzWNMRs4/FD+7p6kC4i1iPXLg=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}