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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'a387f2bf3938821216d898464aab3d901da5f800832e19f1123737611ae91b4e' 
  AND token = 'LgGOliolCIgQ9VdxDlddJrQEbdp+0+1tsAqpGxY/uNE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00032

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}