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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '4ad4d4a79d644266fca92ce30b9e715e54cbfea4e5097f062697a465b8bf270c' 
  AND token = 'R3jgtfpHFJoqcmaqrZrkm8NAceE6E8BdP13+eUgTp/I=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00032

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}