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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'ae525686c4f8329abf2d8292931f0f49a9ed86e4e71b0570230e6732ada72b25' 
  AND token = 'igysaDATEGchQG9qMEz/qpE0mqChjjgmFdGOKlobyFc=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00042

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}