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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '49fa5692280ed8aee885c81ae63669d3cdcf8a7ce4e69b570d726b81a07087a9' 
  AND token = '0KJhaR3BB3p+9OFvR1JlO8YvmuZ1kxrBtuBIWaIQ/ko=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00037

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}