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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '3bc432bdadbee2a709752f57aae223dd2e6b4038dc4606d901d78d9d30508da0' 
  AND token = 'ZjiLiZE6/hbGk79JL7ycUYB9V6+Yi7qLXWR58KtC5gs=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00028

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}