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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '2d9e861741ea532a28a543e84969e668e662131236cef1edb28b7b4341f226fc' 
  AND token = '2AZ6yCvcnEv/ZXdXuhleDhPDnDGAc9zBzmZAGCyRWto=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00059

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}