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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'b2b1c8fd960f7fbe257e8c4c09697e41feb38c08e14665b055b8e38cdcbfec02' 
  AND token = '6fowIbx1MYIZD86108RQlFC8MX/E0iUJn4Z8ToUADjQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}