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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '591927f2ed34687e281a8735053650351bc7d22a35fb4c3b08d8017e4b243c4e' 
  AND token = 'TBNGATH+eSyAxp8yZMqQ+Sb5ucIozWWJwuW1dO/sSuc=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00027

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}