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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '9d1ac80d83add9d1e5121e166c320bfddb8dbf980a45da10e2c769ff7ef87c68' 
  AND token = 'HwkauKnl9nr++xzSLOdyp26XC7Ck9KABznDyRIHsArQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00036

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}