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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'ab1dd3ef2d8e7dcae3629041657c111c64043c749a64bf2480e436669f2d8124' 
  AND token = 'eqV+OjRDEiHFohXMpXZh+0QRJr1bdzcfI0SYL7+490c=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00022

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}