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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '53dd1f7456b813dd365b57b3436e8a62bb609a35cb5f3083b697047a52f2c04f' 
  AND token = 'FPhRH1Xh0qR4v7+uC6OgIeFyFkK31br/aDT5VIu6xfM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00038

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}