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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '5f183038af52a5b223a872c57c24881a07d0d6f9c027853e02dba6457f8888f1' 
  AND token = 'cdbbtbU1oFwmIW+5AYUTXC/HZDin9cmlmscvd6qFbSU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00042

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}