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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'de5fc9021999c1dde2be0ccf520f7e82a3073f59540f7aea083a79398894816c' 
  AND token = 'oPslAJz+G5Z0Otv1u5uT5xDYONCJ6UCcTNpsVEKbEbo=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00029

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}