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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '8b05302d413e7ec98627f6c3cd509cc6f3f67c3a3ec8aa14d2d1cf03615d1abe' 
  AND token = '7Y2b3h2TvOFD+SHYmdx2NBPnlTSqqAtM6Qf30A6eCCk=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00042

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}