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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '431acc72aea6db568834a6dc7179f812670a70dace817fcdf57847d4e5f4cc80' 
  AND token = '7hV2XGXTzIsLcj/3h+UXD+BULuNA4N5eOudEY24QWUo=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00037

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}