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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '46a3d9be2a3aedf4b606c99775f57035db9164b9d36f53e772736167d2847df9' 
  AND token = 'zR+meggE13VfpllkUbjtXR2UYsNsf/tPeaKrbnLsmjk=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00043

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}