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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '835a2e19a965b234aa7153a75840b402332d696b50e30cc3e3684c6d74d4c742' 
  AND token = 'AdPhBZwdiZuVy5VI9Dx/h6PXO+HRUS/0Mdf5Ld/cWes=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00042

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}