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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '60df121ad07c9382f616a190976bf21007fa2fdc9d79e9d18989ce9db66260db' 
  AND token = 'o57kQ2Clm8sWHANdxF4SdUONL9zMRL2oddN8lKTMgdM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00058

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}