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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '4fb2bf519d89ab36787da875f617f561e2f27f9e71d4c02461b4f1066e37f7c8' 
  AND token = '/CqQdJv1UvYr2Tb3oRJzsuTW0ATi3okkUoOzlISICdM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00064

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}