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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '439ba5fed6abfaab0624000d38deabffe9df546b5c1bf860a4ed31699b103dcd' 
  AND token = 'c8cO/BpaIK4SzBSzlYcgW8ZWC2HQQPdC9hqEQ2dTpT0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00055

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}