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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '641a207b65823510a5028f41cdd831f0526462a776b35943136bec4fc758048f' 
  AND token = 'J/utyzAFeCWbinppe2bWAbbI71doBzF5OpvqefV29cE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00044

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}