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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'c2f9fe8e386009bb83a24cb2badaf8792462920c80c619fdd64ae6baa2342ce7' 
  AND token = 'M+j4ZPxZimZSOPsUwDQN3bfV3LyXzuW1hIGYys8v9ko=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00045

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}