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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '66147fa5b194a0df8f9d9aea9a04549ff854387ab9c97c98511d55dca4ce119d' 
  AND token = 'Tjs/D30Ung8c2gKtgDtyTG5lhleh00sn5/lp9Nxa34I=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00027

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}