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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '2fa64f92f18e22e177b2ca8436e4006f1f2da7b8a2d10998c24bdbaef1183412' 
  AND token = 'ZI47x4HhEbej4KVwPCk2ZcWiTitZbl2WAvLJ3WdsCoM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}