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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '78f7484f311b1ece029ffe18bc1d9631ef498d79ab78b9d5a4e875ae40283387' 
  AND token = 'Oh2suFYnp5fB3nBBoXTRqmXijTKRPdO2XbEiaxUkxeI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00051

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}