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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '769991273e2526219402a11cc2d8af3a79a158b9c1a4e24d6b18184eddb04066' 
  AND token = 'zQLteNVs7ZzNY+2DJcQl8PTYGjNKz9lhhydE8n42Th8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00023

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}