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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '4a59b1b8c1c82d3cda81fe7d560d3dc49e050d3b5c987b84e4029c7d19aa7825' 
  AND token = 'DyFXDzD4MHzr8Uu4mMXHZ5cgksBdrNpiFJ9BVEJdqvM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00046

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}