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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '22738ab5d0c05daed2761ab3dae7e8ff603155a374d1cbf5964707950819ac36' 
  AND token = 'WfpMJtkpUvcmBAOvlUL5HHehMDat2hcerIA019t1DCQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00036

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}