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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'a4afd82e7515b1977865ce0410bf50d4e4996b40d2268dd10a90e413147f0b69' 
  AND token = 'RhYqWFfKHTmFW9TVTko0peVWv5QkbPxpsnzcDpYDeD8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00042

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}