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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '8d3a6e2b590b75198ddf02008dde755592171215dc46f053e52d3585bd361798' 
  AND token = '7QpTMWDWzTQ5aMkGInm9yN3cR3b6Jnhe4CG+aLGVwdw=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00055

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}