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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '190cc82389eaf0aeb05b67ff78e9eabf255ac5287059bf885bb9d282bce80150' 
  AND token = 'fG/8qp5Che/eTHAyWjLOfjVM3Qd6OAs1Z4yzKRyAOOU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00031

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}