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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '8ea250a57847cb6e69b0fdb3c0db3680b375faf93cc16fbd8f6e8417d72b9211' 
  AND token = 'ATtLpiOdgta0DRxH2hpvmWfXhZG0BLaZqUcf3G+7MsE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00028

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}