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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '8ddd79c809a106bf0fceaa6f9f02243200befe1e9a6b8614116311a9feca08f3' 
  AND token = 'JRNuhxUnQFSM5pE8zI9GQpddXUiXWTg0D3IvtU6CmYk=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}