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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '4c39060fb5c0d6a60e0c4b2b1875988252e0154cdaa8b9dbb56e12982911024a' 
  AND token = 'gmcF1E2R6Bzt/KMLHGFBAun+WmV4HxaRuzrE8XY0z5Q=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00037

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}