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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'f454438ff841ac7a2604f01d3b6cda013956332d86523a2fc60cfbcee7ff3897' 
  AND token = 'kH6kdnu4DHhoAoJ3SHGqWUzzg/kFWNaTpmUmh7aVHKs=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}