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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'b0845fb2183cc75154c1c17db0c7e3363182fdf9fe76f2c48cbdf6e58fd79b61' 
  AND token = '2zt9ZXbNGOerrPC1sAwdmY6NuRtDBmRnm/y2txRh3d0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00056

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}