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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '00f733c6dabb99ee445a510b2379a06ce444eeefe075e2b2553aff48b80e5732' 
  AND token = '2DuXIId5VZFnaJjZOkjsA3wV25xq8puh2yhZqlpQTpM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00034

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}