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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'd6640fd036457c809099195b238cb4282621d1c7490776f338d753d62c6884b1' 
  AND token = 'emf60h9i537SA6jhg1MLrb+suDMTZxf3trU7VwusYu8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00059

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}