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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'a825b7c1116f36bc228be4b06faba7ce5a7b73f3ac00610cc452134f89d12cbe' 
  AND token = 'ishVVvNgo92Op4F9G6M355brc6blI4RmFfhAb8CiGpE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00046

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}