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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '2c9bd90c1eb04fec0d8d95ff5c5175c38202a375b2e2148853299e1c3df5f1a6' 
  AND token = 'GWllFBmeOvc3zB2I9hMvM0XLjCL8xZF1HlT8RfZfggA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00034

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}