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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '5c6bbe38076b10c3d816f2e584bf859ec064605493c200085d6978f095ae904f' 
  AND token = 'ITYYWqN214Gk4Obui//QQXsyG5+zvgDMbWyb7LCTCtw=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00036

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}