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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'b67a41e1ee24fffaacaf05e692fe5814e6fb869249def63921c2a4ee36f04f41' 
  AND token = '4CjETXzI6CBvxWfd7RMu6V/2tBZWyxEQ0gnz7ft07Ww=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00059

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}