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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '1eabaf9dbfc30665c21cfaae0002b69e4cedeaa4bd0bfe0e213e5e1072140978' 
  AND token = 'D+u5k/MxtP3JcP1stLd9GtiTDTvGl4jggEA5Qt7pyQA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00045

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}